Nephrotoxicity associated with cephalothin administration.

@article{Carling1975NephrotoxicityAW,
  title={Nephrotoxicity associated with cephalothin administration.},
  author={Philip C. Carling and BeldonA. Idelson and A A Casano and Edward A. Alexander and William R. Mccabe},
  journal={Archives of internal medicine},
  year={1975},
  volume={135 6},
  pages={
          797-801
        }
}
Variable degrees of acute renal failure developed in three patients receiving therapy with cephalothin sodium. The course and findings were consistent with acute tubular necrosis of the oliguric and nonoliguric types. One patient had protracted oliguria, a second experienced transient oliguria, and one had normal urine output. All had urinary sediment changes consistent with tubular necrosis, and the two oliguric patients had elevated urine sodium concentrations. No other causes for renal… CONTINUE READING
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