Nephrotoxicity Related to New Therapeutic Compounds

@article{Szeto2005NephrotoxicityRT,
  title={Nephrotoxicity Related to New Therapeutic Compounds},
  author={Cheuk Chun Szeto and Kai Ming Chow},
  journal={Renal Failure},
  year={2005},
  volume={27},
  pages={329 - 333}
}
Toxic nephropathy is an important cause of reversible renal injury. This article focuses on the nephrotoxicity of several new therapeutic compounds. Selective cyclooxygenase-2 inhibitor is associated with sodium retention, hypertension, ankle edema, and acute renal failure. The incidence of renal complication is similar to conventional nonsteroidal anti-inflammatory drugs. Bisphosphonates, especially when used in high dose for prolonged duration, can cause toxic acute tubular necrosis and renal… 
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