Nephrotic syndrome associated with hemophagocytic syndrome.

  title={Nephrotic syndrome associated with hemophagocytic syndrome.},
  author={Olivier Thaunat and Michel Delahousse and Fadi Fakhouri and Frank Martinez and J. John Stephan and L H No{\"e}l and Alexandre Karras},
  journal={Kidney international},
  volume={69 10},
Hemophagocytic syndrome (HPS) is defined by bone marrow and organ infiltration by activated, nonmalignant macrophages, which phagocytose blood cells. The clinical spectrum of HPS is broad, but renal involvement has rarely been investigated. We report a previously unknown renal manifestation of HPS: nephrotic syndrome. This multicentric retrospective study included patients fulfilling the following criteria: (i) no history of nephropathy; (ii) HPS diagnosis with histologic evidence of… CONTINUE READING
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