Nephroprotective action of sirtuin 1 (SIRT1)


Sirtuins, silent information regulator 2 (Sir 2) proteins, belong to the family of NAD+-dependent enzymes with deacetylase or mono-ADP-ribosyltransferase activity. These enzymes are responsible for processes of DNA repair or recombination, chromosomal stability and gene transcription. In mammals, sirtuins occur in seven varieties, from 1 to 7 (SIRT1–SIRT7… (More)
DOI: 10.1007/s13105-013-0268-1


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@article{PolakJonkisz2013NephroprotectiveAO, title={Nephroprotective action of sirtuin 1 (SIRT1)}, author={Dorota Polak-Jonkisz and Krystyna Laszki-Szczachor and Leopold R Rehan and Witold Pilecki and Henryk Filipowski and Malgorzata Sobieszczanska}, journal={Journal of Physiology and Biochemistry}, year={2013}, volume={69}, pages={957-961} }