Nephron morphometry in mice and rats using tomographic microscopy.

  title={Nephron morphometry in mice and rats using tomographic microscopy.},
  author={Robyn F. R. Letts and Xiao-Yue Zhai and Charita Bhikha and Birgitte L Grann and Nicklas B Blom and Jesper Skovhus Thomsen and David M. Rubin and Erik Ils\o Christensen and A. K. Andreasen},
  journal={American journal of physiology. Renal physiology},
  volume={312 1},
The aim was to quantify the glomerular capillary surface area, the segmental tubular radius, length, and area of single nephrons in mouse and rat kidneys. Multiple 2.5-µm-thick serial Epon sections were obtained from three mouse and three rat kidneys for three-dimensional reconstruction of the nephron tubules. Micrographs were aligned for each kidney, and… CONTINUE READING