Nephritogenicity of proteoglycans. III. Mechanism of immune deposit formation.

Abstract

Administration of antibody, directed against glomerular basement membrane (GBM) heparan sulfate-proteoglycan, into a presensitized rat results in the induction of membranous nephropathy with subepithelial immune-complex deposits. In this investigation, we examined the mechanisms responsible for the formation of subepithelial immune-complex deposits in the… (More)

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@article{Makino1988NephritogenicityOP, title={Nephritogenicity of proteoglycans. III. Mechanism of immune deposit formation.}, author={Hirofumi Makino and Brigitte Lelongt and Yashpal S. Kanwar}, journal={Kidney international}, year={1988}, volume={34 2}, pages={209-19} }