Nep98p is a component of the yeast spindle pole body and essential for nuclear division and fusion.

@article{Nishikawa2003Nep98pIA,
  title={Nep98p is a component of the yeast spindle pole body and essential for nuclear division and fusion.},
  author={Shuh-ichi Nishikawa and Yumiko Terazawa and Takeshi Nakayama and Aiko Hirata and Tadashi Makio and Toshiya Endo},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 11},
  pages={9938-43}
}
During the mating of yeast Saccharomyces cerevisiae, two haploid nuclei fuse to produce a diploid nucleus. This process requires the functions of BiP/Kar2p, a member of the Hsp70 family in the endoplasmic reticulum, and its partner protein, Jem1p. To investigate further the role of BiP and Jem1p in nuclear fusion, we screened for partner proteins for Jem1p by the yeast two-hybrid system and identified Nep98p. Nep98p is an essential integral membrane protein of the nuclear envelope and is… CONTINUE READING