The association between macular pigment optical density and CFH, ARMS2, C2/BF, and C3 genotype.
- Edward Loane, John M Nolan, Gareth J McKay, Stephen Beatty
- Experimental eye research
- 2011
Highly Influenced
7 Excerpts
Neovascular Age-Related Macular Degeneration Risk Based on CFH, LOC387715/HTRA1, and Smoking
- Published 2007 in PLoS medicine
Abstract
BACKGROUND
Age-related macular degeneration (AMD) is the major cause of blindness in the elderly. Those with the neovascular end-stage of disease have irreversible loss of central vision. AMD is a complex disorder in which genetic and environmental factors play a role. Polymorphisms in the complement factor H (CFH) gene, LOC387715, and the HTRA1 promoter… (More)