Neopterin as a new biochemical marker in the clinical assessment of ulcerative colitis.

@article{Niederwieser1985NeopterinAA,
  title={Neopterin as a new biochemical marker in the clinical assessment of ulcerative colitis.},
  author={Dietger Niederwieser and Dietmar Fuchs and Asno Hausen and Gerd Judmaier and Gilbert Reibnegger and Helmut Wachter and Christoph Huber},
  journal={Immunobiology},
  year={1985},
  volume={170 4},
  pages={320-6}
}
In previous publications we showed that neopterin, a pyrazino-pyrimidin compound, represents a biochemical marker for the assessment of cellular immune responses. We thought that the evaluation of this marker molecule might enable insight into the activity of cellular immune responses underlying ulcerative colitis (UC). Evaluation of urinary neopterin excretion in 25 consecutive untreated UC patients revealed striking correlations between neopterin levels and the severity of disease: elevated… CONTINUE READING