Neoplastic transformation of guinea pig fetal cells in culture induced by chemical carcinogens.

@article{Evans1975NeoplasticTO,
  title={Neoplastic transformation of guinea pig fetal cells in culture induced by chemical carcinogens.},
  author={Christopher H. Evans and Joseph A Dipaolo},
  journal={Cancer research},
  year={1975},
  volume={35 4},
  pages={1035-44}
}
Twenty-four cell strains derived from freshly isolated diploid strain 2 guinea pig fetal cells exposed in utero or directly in culture to a carcinogenic or noncarcinogenic chemical were evaluated during 4 to 24 months of continuous cultivation. Morphological alterations in carcinogen, i.e., benzo(a)pyrene-, 7,12-dimethylbenz(a)anthracene-, 3-methylcholanthrene-, N-methyl-N'-nitro-N-nitrosoguanidine-, diethylnitrosamine-, aflatoxin B1-, or N-acetoxyacetylaminofluorene-treated cultures were seen… CONTINUE READING

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