Neoplastic response of mouse tissues during perinatal age periods and its significance in chemical carcinogenesis.

@article{Vesselinovitch1979NeoplasticRO,
  title={Neoplastic response of mouse tissues during perinatal age periods and its significance in chemical carcinogenesis.},
  author={Stan D Vesselinovitch and K Narasimha Rao and N. Mihailovich},
  journal={National Cancer Institute monograph},
  year={1979},
  volume={51},
  pages={239-50}
}
A series of studies pertaining to perinatal carcinogenesis have been reviewed. Their main objective was development and definition of a sensitivity biologic model for carcinogenicity screening. Data were summarized on factors modifying the carcinogenic response of various tissues following transplacental, neonatal-infant, or adult exposure of (B57BL/6J X C3HeB/FeJ)F1 mice to a single administration of ENU. In addition, tumor response of mice treated during specific perinatal age periods with… CONTINUE READING

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