Neoplastic fibroblasts sensitive to the growth inhibition by homologous cells but insensitive to inhibition by parent normal cells.

Abstract

3H-thymidine labelling and autoradiography were used to compare density dependent inhibition of growth in the cultures of two transformed lines of hamster fibroblasts and in primary cultures of their parent normal cells. Similar manifestations of density dependent inhibition were found in the isolated cultures of normal and neoplastic cells: at saturation… (More)
DOI: 10.1038/bjc.1975.94

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