Neoplastic epithelial cells in a subset of human thymomas express the B cell-associated CD20 antigen.

@article{Chilosi1992NeoplasticEC,
  title={Neoplastic epithelial cells in a subset of human thymomas express the B cell-associated CD20 antigen.},
  author={Marco Chilosi and Paola Castelli and Guido Martignoni and Giovanni Pizzolo and Ettore Montresor and Fabio F. Facchetti and Mauro Truini and Aldo Mombello and Maurizio Lestani and Aldo Scarpa},
  journal={The American journal of surgical pathology},
  year={1992},
  volume={16 10},
  pages={988-97}
}
A series of 36 human thymomas have been immunohistochemically analyzed using a panel of antibodies recognizing B-cell markers including CD20. Most thymomas exhibiting the cortical pattern, according to the criteria of Marino and Muller-Hermelink, were characterized by areas of medullary differentiation containing variable numbers of CD20+ B lymphocytes, thus mimicking the medulla of normal thymus. On the other hand, B cells were absent or rare in thymomas recognized as mixed using the same… CONTINUE READING
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