[Neonatal septicemias: biological diagnosis and antibiotherapy. Apropos of a series of 46 cases].

Abstract

The records of 46 neonates with proven septicaemia were retrospectively studied. Patients could be divided in 2 groups: in group 1 (21 infants) a positive blood culture was obtained before one day of life; in group 2 (25 infants) a positive blood culture was obtained between days 1 and 28. The sensitivity of 9 chemical and bacteriological tests and the efficacy of the initial antibiotic treatment were examined in both groups. Of the 21 germs isolated in patients from group 1, 86% were Gram positive bacteria and 95% were susceptible to ampicillin. Of the 26 germs isolated in patients from group 2, 80% were Gram negative enteric bacteria and 86% were susceptible to cefotaxime. Bacterial tests (gastric aspiration, antigen detection, feces culture) had a better sensibility than biochemical tests (C reactive protein, orosomucoid, fibrinogen).

Cite this paper

@article{Trluyer1991NeonatalSB, title={[Neonatal septicemias: biological diagnosis and antibiotherapy. Apropos of a series of 46 cases].}, author={J M Tr{\'e}luyer and Y. Bompard and A Gantzer and Andr{\'e} Chastel and C. Aufrant}, journal={Archives françaises de pédiatrie}, year={1991}, volume={48 5}, pages={317-21} }