Neonatal seizures with tonic clonic sequences and poor developmental outcome.

  title={Neonatal seizures with tonic clonic sequences and poor developmental outcome.},
  author={Bernhard Schmitt and Gabriele Christine Wohlrab and Thomas K. Sander and Ortrud K Steinlein and Beatrice F. Latal Hajnal},
  journal={Epilepsy research},
  volume={65 3},
Seizures consisting of a tonic followed by a clonic phase have rarely been described in neonates and are not included in the current classifications of neonatal seizures. Our video archive of 105 neonates with seizures or suspected seizures revealed six neonates with such tonic clonic or tonic myoclonic sequences. Two of those neonates had pyridoxine dependent seizures. The other four neonates had drug refractory seizures and demonstrated similarities in electro-clinical pattern, clinical… CONTINUE READING
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