Neonatal procedural pain exposure predicts lower cortisol and behavioral reactivity in preterm infants in the NICU

@article{Grunau2005NeonatalPP,
  title={Neonatal procedural pain exposure predicts lower cortisol and behavioral reactivity in preterm infants in the NICU},
  author={Ruth E. Grunau and Liisa Holsti and David W. Haley and Tim F Oberlander and Wayne Yu},
  journal={Pain},
  year={2005},
  volume={113},
  pages={293-300}
}
Data from animal models indicate that neonatal stress or pain can permanently alter subsequent behavioral and/or physiological reactivity to stressors. However, cumulative effects of pain related to acute procedures in the neonatal intensive care unit (NICU) on later stress and/or pain reactivity has received limited attention. The objective of this study is to examine relationships between prior neonatal pain exposure (number of skin breaking procedures), and subsequent stress and pain… CONTINUE READING

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