Neonatal phenobarbital administration results in increased cytochrome P450-dependent monooxygenase activity in adult male and female rats.

@article{Bagley1983NeonatalPA,
  title={Neonatal phenobarbital administration results in increased cytochrome P450-dependent monooxygenase activity in adult male and female rats.},
  author={Daniel M Bagley and J. Robert Hayes},
  journal={Biochemical and biophysical research communications},
  year={1983},
  volume={114 3},
  pages={1132-7}
}
The effects of neonatal exposure to phenobarbital during the first five days after birth on the enzymatic activity of the adult male and female rat liver P450-dependent monooxygenase system were investigated. Although liver weight per 100 grams of body weight and total hepatic microsomal protein content were not altered in adult rats treated neonatally with… CONTINUE READING