Neonatal nicotine exposure alters hippocampal EEG and event-related potentials (ERPs) in rats.

@article{Slawecki2000NeonatalNE,
  title={Neonatal nicotine exposure alters hippocampal EEG and event-related potentials (ERPs) in rats.},
  author={Craig J Slawecki and Jennifer D. Thomas and Edward P. Riley and Cindy L Ehlers},
  journal={Pharmacology, biochemistry, and behavior},
  year={2000},
  volume={65 4},
  pages={711-8}
}
A consensus is forming that nicotine can damage the developing rat central nervous system. However, few studies have assessed the electrophysiological effects of neonatal nicotine exposure in rodents in brain regions known to be sensitive to the teratogenic properties of nicotine. In a previous study it was reported that 1.0 and 4.0 mg/kg/day nicotine exposure from postnatal days 4-9, a developmental period corresponding to human third-trimester exposure, significantly altered hippocampal event… CONTINUE READING
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