Neonatal neurosteroid levels are determinant in shaping adult prepulse inhibition response to hippocampal allopregnanolone in rats.

@article{Darbra2013NeonatalNL,
  title={Neonatal neurosteroid levels are determinant in shaping adult prepulse inhibition response to hippocampal allopregnanolone in rats.},
  author={S{\`o}nia Darbra and Laura M{\`o}dol and Monique Vall{\'e}e and M G{\'o}mez Pallar{\`e}s},
  journal={Psychoneuroendocrinology},
  year={2013},
  volume={38 8},
  pages={1397-406}
}
Diverse studies indicate that the alteration of the physiological levels of neurosteroids in early neonatal phases provokes alterations in the maturation of certain cerebral structures. Allopregnanolone (ALLO) has important modulatory effects in the hippocampus during the postnatal period where the adult pattern of inhibitory transmission is being established. In order to study whether endogenous neonatal ALLO levels would be a determinant parameter involved in mediating adult hippocampal GABAA… CONTINUE READING