Neonatal necrotizing enterocolitis, a disease of the immature intestinal mucosal barrier.

@article{Israel1994NeonatalNE,
  title={Neonatal necrotizing enterocolitis, a disease of the immature intestinal mucosal barrier.},
  author={Esther Jacobowitz Israel},
  journal={Acta paediatrica (Oslo, Norway : 1992). Supplement},
  year={1994},
  volume={396},
  pages={27-32}
}
Necrotizing enterocolitis (NEC) is an enigmatic process in that one single etiologic factor has been sought and not found. Epidemiologic studies suggest that immaturity of the host plays a very important role. This article reviews the intestinal host defense system and its immature nature early in life in animal models and humans and suggests that it is this immaturity, along with other factors, which allows for the proliferation and invasion of antigens and organism, and the subsequent… CONTINUE READING

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