Neonatal lupus erythematosus.

  title={Neonatal lupus erythematosus.},
  author={Lela A. Lee},
  journal={The Journal of investigative dermatology},
  volume={100 1},
  • Lela A. Lee
  • Published 1993 in The Journal of investigative dermatology
Neonatal lupus erythematosus (NLE) is an autoimmune disease whose major findings are subacute cutaneous lupus erythematosus (SCLE) skin lesions and congenital heart block. Babies have maternal anti-Ro/SSA, anti-La/SSB, or anti-U1RNP autoantibodies. Anti-Ro/SSA are the predominant autoantibodies, having been found in about 95% of cases. The autoantibodies pass through the placenta from mother to child. Skin disease resolves at about the time that maternal autoantibodies can no longer be detected… CONTINUE READING
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