Neonatal lung side population cells demonstrate endothelial potential and are altered in response to hyperoxia-induced lung simplification.

@article{Irwin2007NeonatalLS,
  title={Neonatal lung side population cells demonstrate endothelial potential and are altered in response to hyperoxia-induced lung simplification.},
  author={David C Irwin and Klaus C. Helm and Neil C Campbell and Masatoshi Imamura and Karen M. Fagan and Julie Harral and Michelle Carr and Katharine A Young and Dwight J. Klemm and Sarah A L Gebb and Edward C. Dempsey and James West and Susan K. Majka},
  journal={American journal of physiology. Lung cellular and molecular physiology},
  year={2007},
  volume={293 4},
  pages={
          L941-51
        }
}
Lung side population (SP) cells are resident lung precursor cells with both epithelial and mesenchymal potential that are believed to play a role in normal lung development and repair. Neonatal hyperoxic exposure impairs lung development leading to a long-term decrease in gas exchange surfaces. The hypothesis that lung SP cells are altered during impaired lung development has not been studied. To address this issue, we characterized the endothelial potential of neonatal lung SP and subsets of… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 35 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 62 REFERENCES

CD 34 / CD 133  / VEGFR 2  EPC subpopulation its potent vasoregenerative capacities

  • EB Freidrich, K Walenta, J Scharlau, G Nickenig, N Werner
  • Circ Res
  • 2006

Similar Papers

Loading similar papers…