Neonatal kidney size and function in preterm infants: what is a true estimate of glomerular filtration rate?

@article{Abitbol2014NeonatalKS,
  title={Neonatal kidney size and function in preterm infants: what is a true estimate of glomerular filtration rate?},
  author={Carolyn L Abitbol and Wacharee Seeherunvong and Marta G Galarza and Chryso Pefkaros Katsoufis and Denise Francoeur and Marissa J Defreitas and Alcia Edwards-Richards and Vimal Master Sankar Raj and Jayanthi J. Chandar and Shahnaz Duara and Salih Y Yasin and Gast{\`o}n E. Zilleruelo},
  journal={The Journal of pediatrics},
  year={2014},
  volume={164 5},
  pages={1026-1031.e2}
}
OBJECTIVES To distinguish between cystatin C (CysC) and creatinine (Cr) as markers of estimated glomerular filtration rate (eGFR) in preterm infants and to correlate eGFR with total kidney volume (TKV) as a surrogate of nephron mass. STUDY DESIGN Sixty preterm (<37 weeks' gestational age [GA]) and 40 term infants were enrolled at birth. Serum Cr and CysC levels were assessed during the first week of life. Renal ultrasounds were performed to assess kidney dimensions with calculation of the TKV… CONTINUE READING