Neonatal fluoxetine exposure alters motor performances of adolescent rats.

@article{Lee2012NeonatalFE,
  title={Neonatal fluoxetine exposure alters motor performances of adolescent rats.},
  author={Li-Jen Lee and Lukas Jyuhn-Hsiarn Lee},
  journal={Developmental neurobiology},
  year={2012},
  volume={72 8},
  pages={
          1122-32
        }
}
Growing evidence from human and animal studies has shown adverse consequences of maternal usage of antidepressants in their newborn babies. To study the effects of early antidepressant exposure on motor function later in life, we treated neonatal rat pups with fluoxetine (FLX), a selective serotonin reuptake inhibitor (SSRI)-type antidepressant, from the day of birth to postnatal day 4 and examined motor performance during adolescence. FLX-treated rats had reduced locomotor activities in an… CONTINUE READING

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