• DOI:10.1016/j.bbr.2016.04.047
Corpus ID: 6351778

Neonatal finasteride administration decreases dopamine release in nucleus accumbens after alcohol and food presentation in adult male rats

@article{Llid2016NeonatalFA,
  title={Neonatal finasteride administration decreases dopamine release in nucleus accumbens after alcohol and food presentation in adult male rats},
  author={A. Llid{\'o} and I. Bartolom{\'e} and S. Darbra and M. Pallar{\'e}s},
  journal={Behavioural Brain Research},
  year={2016},
  volume={309},
  pages={44-50}
}

A. Llidó, I. Bartolomé, +1 author M. Pallarés

Published 2016

Medicine

Behavioural Brain Research

Endogenous levels of the neurosteroid (NS) allopregnanolone (AlloP) during neonatal stages are crucial for the correct development of the central nervous system (CNS). In a recent work we reported that the neonatal administration of AlloP or finasteride (Finas), an inhibitor of the enzyme 5α-reductase needed for AlloP synthesis, altered the voluntary consumption of ethanol and the ventrostriatal dopamine (DA) levels in adulthood, suggesting that neonatal NS manipulations can increase alcohol… CONTINUE READING

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