Neonatal ethanol and nicotine exposure causes locomotor activity changes in preweanling animals

@article{Gilbertson2005NeonatalEA,
  title={Neonatal ethanol and nicotine exposure causes locomotor activity changes in preweanling animals},
  author={Rebecca J. Gilbertson and Susan J Barron},
  journal={Pharmacology Biochemistry and Behavior},
  year={2005},
  volume={81},
  pages={54-64}
}
Sprague-Dawley rats were used to investigate the effects of neonatal ethanol (ETOH) and nicotine (NIC) exposure on activity levels in preweanling offspring. Male and female pups received daily oral intubations of ethanol ((ETOH) 5 g/kg/day), nicotine ((NIC) 12 mg/kg/day), ethanol and nicotine ((ETOH+NIC) 5 g/kg/day+12 mg/kg/day) or isocaloric maltose (control) on either postnatal days (PND) 1-7 or PND 8-14. A non-treated control group was also included. Peak blood ethanol concentrations (BECs… CONTINUE READING
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