Neonatal diagnosis of severe combined immunodeficiency leads to significantly improved survival outcome: the case for newborn screening.

@article{Brown2011NeonatalDO,
  title={Neonatal diagnosis of severe combined immunodeficiency leads to significantly improved survival outcome: the case for newborn screening.},
  author={Lucinda Brown and Jinhua Xu-Bayford and Zoe Allwood and Mary Anne Slatter and Andrew Cant and E. Graham Davies and Paul A. Veys and Andrew R Gennery and Hubert Bobby Gaspar},
  journal={Blood},
  year={2011},
  volume={117 11},
  pages={3243-6}
}
Severe combined immunodeficiency (SCID) carries a poor prognosis without definitive treatment by hematopoietic stem cell transplantation. The outcome for transplantation varies and is dependent on donor status and the condition of the child at the time of transplantation. Diagnosis at birth may allow for better protection of SCID babies from infection and improve transplantation outcome. In this comparative study conducted at the 2 designated SCID transplantation centers in the United Kingdom… CONTINUE READING

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