Neonatal dexamethasone on day 7 causes mild hyperactivity and cerebellar stunting.

@article{Ferguson1999NeonatalDO,
  title={Neonatal dexamethasone on day 7 causes mild hyperactivity and cerebellar stunting.},
  author={Sherry Ann Ferguson and R. Robert Holson},
  journal={Neurotoxicology and teratology},
  year={1999},
  volume={21 1},
  pages={71-6}
}
To investigate the effects of glucocorticoid treatment on central nervous system development, rats were injected with dexamethasone (DEX) (1-3 mg/kg) on postnatal day (PND) 3 or 7. DNA and protein content and concentration were measured in the cerebellum and hippocampus on PND 28 and 112. Whole and regional brain weights were measured at PND 28, 84, and 112. Nest odor preference (PND 10-11), open field activity (PND 18-21), running wheel activity (PND 50-56), and complex maze performance (PND… CONTINUE READING