Neonatal amygdala lesions and juvenile isolation in the rat: differential effects on locomotor and social behavior later in life.

@article{Diergaarde2004NeonatalAL,
  title={Neonatal amygdala lesions and juvenile isolation in the rat: differential effects on locomotor and social behavior later in life.},
  author={Leontien Diergaarde and Mirjam Gerrits and Andrea Stuy and Berry M. Spruijt and Jan M van Ree},
  journal={Behavioral neuroscience},
  year={2004},
  volume={118 2},
  pages={298-305}
}
Pervasive developmental disorders such as autism are characterized by deficits in social interaction and communication. Disturbed development of limbic structures such as the amygdala might underlie these deficits. The authors examined the effects of amygdala lesions on Postnatal Day 7 and juvenile isolation (2 weeks of individual housing during Weeks 4 and 5 of life) on rat locomotor and social activity later in life. Before puberty, but more pronounced after puberty, lesioned rats displayed… CONTINUE READING

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