Neonatal Thyroid Function in Seveso 25 Years after Maternal Exposure to Dioxin

  title={Neonatal Thyroid Function in Seveso 25 Years after Maternal Exposure to Dioxin},
  author={Andrea A. Baccarelli and Sara Mariasole Giacomini and Carlo Corbetta and Maria Teresa Landi and Matteo Bonzini and Dario Consonni and Paolo Grillo and Donald J. Patterson and Angela Cecilia Pesatori and Pier Alberto Bertazzi},
  journal={PLoS Medicine},
  pages={396 - 404}
BACKGROUND Neonatal hypothyroidism has been associated in animal models with maternal exposure to several environmental contaminants; however, evidence for such an association in humans is inconsistent. We evaluated whether maternal exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a persistent and widespread toxic environmental contaminant, is associated with modified neonatal thyroid function in a large, highly exposed population in Seveso, Italy. METHODS AND FINDINGS Between 1994 and… CONTINUE READING


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