Neonatal Herpes Simplex Virus Infections in Canada: Results of a 3-Year National Prospective Study

@article{Kropp2006NeonatalHS,
  title={Neonatal Herpes Simplex Virus Infections in Canada: Results of a 3-Year National Prospective Study},
  author={Rhonda Y. Kropp and Thomas Wong and Loretta Ann Cormier and Allison Ringrose and Sandra Burton and Joanne E. Embree and Marc Steben},
  journal={Pediatrics},
  year={2006},
  volume={117},
  pages={1955 - 1962}
}
OBJECTIVE. The goal was to determine incidence, determinants, and morbidity and mortality rates of neonatal herpes simplex virus infections in Canada. METHODS. From October 1, 2000, to September 30, 2003, reports of neonatal herpes simplex virus infection were solicited actively from all Canadian pediatricians and pediatric subspecialists on a monthly basis. RESULTS. Fifty-eight cases of neonatal herpes simplex virus were reported (5.9 cases per 100000 live births). Cesarean section was… Expand
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References

SHOWING 1-10 OF 47 REFERENCES
Neonatal herpes simplex virus infection: a report of 43 patients.
TLDR
This study underlines the occurrence of intrauterine transmission of herpes virus, infections with neurologic manifestations, early symptomatology and the need for prompt diagnosis, brain biopsy in selected patients and antiviral therapy in neonates with herpes virus infection. Expand
Neonatal herpes simplex virus infection in the British Isles.
This study was set up to estimate the incidence of neonatal herpes simplex virus (HSV) infection in the British Isles, and to document the outcome of neonatal infection. Paediatricians reported casesExpand
Natural history of neonatal herpes simplex virus infections in the acyclovir era.
TLDR
Comparisons between patients treated in the periods between 1981-1988 and 1989-1997 according to extent of disease revealed that the mean time between the onset of disease symptoms and initiation of therapy has not changed significantly from the early 1980s to the late 1990s, demonstrating that no progress has been made in decreasing the interval between onset of HSV symptoms and initiated antiviral therapy. Expand
Herpes simplex virus type 1 as a cause of genital herpes: impact on surveillance and prevention.
TLDR
The data suggest that seroprevalence studies based solely on HSV-2 type-specific assays underestimate overall prevalence of genital HSV infection. Expand
Neonatal herpes infection: diagnosis, treatment and prevention.
TLDR
Since most neonatal infections are acquired from contact with infected maternal genital tract secretions, potential preventative strategies include: Caesarean delivery, serologic screening of pregnant women, prophylactic acyclovir and vaccination. Expand
Reasons for the absence of a history of recurrent genital infections in mothers of neonates infected with herpes simplex virus.
TLDR
The discrepancy in the HSV neutralization titers of the mothers of infected infants suggests that the mothers may have had a rise in titer late in pregnancy or that placental transport of antibody was limited, and that the infected infants had titers fourfold lower than their mother's titer than the 16 infants exposed to HSV who remained uninfected. Expand
Could neonatal disseminated herpes simplex virus infections be treated earlier?
TLDR
HSV infection should be considered in the differential diagnosis of the acutely unwell neonate, and effective antiviral therapies exist but are often not started early in the clinical course. Expand
Acyclovir prophylaxis in late pregnancy prevents recurrent genital herpes and viral shedding.
  • S. Braig, D. Luton, +4 authors J. Oury
  • Medicine
  • European journal of obstetrics, gynecology, and reproductive biology
  • 2001
TLDR
The findings underline the value of antiviral prophylaxis in late pregnancy for women with a known history of genital herpes, because it is not applicable to patients with no known clinical history but may excrete the virus. Expand
Neonatal herpes simplex: clinical findings and outcome in relation to type of maternal infection
In 39 mothers of children with neonatal herpes simplex virus infection, maternal infection was serologically characterized retrospectively and was related to maternal clinical symptoms and to theExpand
Changing presentation of herpes simplex virus infection in neonates.
TLDR
For neonates with CNS or disseminated infection, disease duration and frequency of prematurity were significantly decreased in the second period, as was the frequency of skin vesicles for newborns with SEM or dissemination infection. Expand
...
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2
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5
...