Neonatal Exposure to Brominated Flame Retardant BDE-47 Reduces Long-Term Potentiation and Postsynaptic Protein Levels in Mouse Hippocampus

@inproceedings{Dingemans2007NeonatalET,
  title={Neonatal Exposure to Brominated Flame Retardant BDE-47 Reduces Long-Term Potentiation and Postsynaptic Protein Levels in Mouse Hippocampus},
  author={Milou M. L. Dingemans and Geert M. J. Ramakers and Fabrizio Gardoni and Regina G.D.M. van Kleef and {\AA}ke Lennart Bergman and Monica di Luca and Martin van den Berg and Remco H.S. Westerink and Henk P. M. Vijverberg},
  booktitle={Environmental health perspectives},
  year={2007}
}
BACKGROUND Increasing environmental levels of brominated flame retardants raise concern about possible adverse effects, particularly through early developmental exposure. OBJECTIVE The objective of this research was to investigate neurodevelopmental mechanisms underlying previously observed behavioral impairments observed after neonatal exposure to polybrominated diphenyl ethers (PBDEs). METHODS C57Bl/6 mice received a single oral dose of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) on… CONTINUE READING
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