Neoadjuvant radiotherapy for locally advanced and high-risk prostate cancer

@article{Thoms2011NeoadjuvantRF,
  title={Neoadjuvant radiotherapy for locally advanced and high-risk prostate cancer},
  author={John Thoms and Jayant Sastri Goda and Alexender R. Zlotta and Neil E. Fleshner and Theodorus H. van der Kwast and St{\'e}phane Supiot and Padraig Richard Warde and Robert G. Bristow},
  journal={Nature Reviews Clinical Oncology},
  year={2011},
  volume={8},
  pages={107-113}
}
Men presenting with high-risk or locally advanced prostate cancer may benefit from a combination of radiotherapy and surgery to maximize local control. Adjuvant radiotherapy following surgery has improved biochemical progression-free survival, metastasis-free survival, lengthened the time to hormone therapy use and improved overall survival in three randomized-phase III trials. One surprising result of the Southwest Oncology Group (SWOG) 8794 trial and the European Organisation for Research and… CONTINUE READING
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Phase I study of preoperative radiation and docetaxel for high‐risk prostate cancer

  • M. Garzotto, A. Hung, T. F. Beer, P. Farris
  • Int. J. Radiat. Oncol. Biol. Phys
  • 2009
Highly Influential
1 Excerpt

Outcome of surgery for clinical REviEWS nrclinonc_207_FEB11.indd

  • C. Y. Hsu, S. Joniau, R. Oyen, T. Roskams, H. Van Poppel
  • Eur. Urol
  • 2011

Long‐term follow‐up of 3‐month neoadjuvant hormone therapy before radical prostatectomy in a randomized trial

  • Yee, S D.
  • BJU Int. 105,
  • 2010

Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer

  • Reid, H A.
  • Br. J. Cancer 102,
  • 2010

A phase I trial of pre ‐ operative radiotherapy for prostate cancer : clinical and translational studies

  • S. Supiot
  • Radiother . Oncol .
  • 2009

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