Neoadjuvant plus adjuvant chemotherapy benefits overall survival of locally advanced gastric cancer.

@article{Chen2011NeoadjuvantPA,
  title={Neoadjuvant plus adjuvant chemotherapy benefits overall survival of locally advanced gastric cancer.},
  author={Xin-zu Chen and Kun Yang and Jie Liu and Xiao-Long Chen and Jian-Kun Hu},
  journal={World journal of gastroenterology},
  year={2011},
  volume={17 40},
  pages={
          4542-4
        }
}
Neoadjuvant chemotherapy (NAC) has drawn more attention to the treatment of locally advanced gastric cancer (AGC) in the current multidisciplinary treatment model. EORTC trial 40954 has recently reported that NAC plus surgery without postoperative adjuvant chemotherapy could not benefit the locally AGC patients in their overall survival. We performed a meta-analysis of 10 studies including 1518 gastric cancer patients. Stratified subgroups were NAC plus surgery and NAC plus both surgery and… CONTINUE READING
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