Neoadjuvant-intensified treatment for rectal cancer: time to change?

  title={Neoadjuvant-intensified treatment for rectal cancer: time to change?},
  author={Daniela Musio and Francesca De Felice and Nadia Bulzonetti and Roberta Guarnaccia and Rossella Caiazzo and Caterina Bangrazi and Nicola Raffetto and Vincenzo Tombolini},
  journal={World journal of gastroenterology},
  volume={19 20},
AIM To investigate whether neoadjuvant-intensified radiochemotherapy improved overall and disease-free survival in patients with locally advanced rectal cancer. METHODS Between January 2007 and December 2011, 80 patients with histologically confirmed rectal adenocarcinoma were enrolled. Tumors were clinically classified as either T3 or T4 and by the N stage based on the presence or absence of positive regional lymph nodes. Patients received intensified combined modality treatment, consisting… CONTINUE READING