Neoadjuvant chemotherapy with FOLFOX: improved outcomes in Chinese patients with locally advanced gastric cancer.

@article{Li2012NeoadjuvantCW,
  title={Neoadjuvant chemotherapy with FOLFOX: improved outcomes in Chinese patients with locally advanced gastric cancer.},
  author={Zi-yu Li and Cherry E. Koh and Zhao-de Bu and Ai-wen Wu and Lian-hai Zhang and Xiao-jiang Wu and Qi Wu and Xiang-long Zong and Hui Ren and Lei Tang and Xiaopeng Zhang and Ji-you Li and Ying Hu and Lin Shen and Jiafu Ji},
  journal={Journal of surgical oncology},
  year={2012},
  volume={105 8},
  pages={793-9}
}
BACKGROUND Although the role of peri-operative chemotherapy is established in the treatment of locally advanced gastric cancer, the optimal regime remains to be determined. FOLFOX has been used in palliative setting with good response rates but its role in a neoadjuvant setting is not well established. METHODS This is a prospective non-randomized study comparing peri-operative FOLFOX versus adjuvant FOLFOX in patients with resectable locally advanced gastric cancer. Response to chemotherapy… CONTINUE READING
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