Neoadjuvant chemotherapy and resection for initially irresectable colorectal liver metastases.

@article{Capussotti2006NeoadjuvantCA,
  title={Neoadjuvant chemotherapy and resection for initially irresectable colorectal liver metastases.},
  author={Lorenzo Capussotti and Andrea Muratore and Maria Maddalena Mulas and Paolo Massucco and Massimo Aglietta},
  journal={The British journal of surgery},
  year={2006},
  volume={93 8},
  pages={1001-6}
}
BACKGROUND Hepatic surgery is the treatment of choice for resectable colorectal liver metastases. Neoadjuvant chemotherapy can downstage the tumour and enable surgery in up to 38 per cent of patients whose tumours were initially considered irresectable. METHODS This prospective study included 150 patients who underwent hepatic resection over a 4-year period. One hundred and sixteen patients had resection without neoadjuvant chemotherapy (group 1) and 34 had chemotherapy before liver surgery… CONTINUE READING