Neoadjuvant chemotherapy and primary-first approach for rectal cancer with synchronous liver metastases.

@article{Gall2014NeoadjuvantCA,
  title={Neoadjuvant chemotherapy and primary-first approach for rectal cancer with synchronous liver metastases.},
  author={Tamara M.H. Gall and Mohamed Basyouny and Adam E Frampton and Ara Darzi and Paul Ziprin and Peter Dawson and Paraskeva Paraskeva and N Habib and Duncan R. C. Spalding and Susan Jane Cleator and Charles Lowdell and Long Richard Jiao},
  journal={Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland},
  year={2014},
  volume={16 6},
  pages={O197-205}
}
AIM Up to a quarter of patients with rectal cancer have synchronous liver metastases at the time of diagnosis. This is a predictor of poor outcome. There are no standardized guidelines for treatment. We reviewed the outcomes of our patients with synchronous rectal liver metastases treated with a curative intent by neoadjuvant chemotherapy with or without chemoradiotherapy followed by resection of the primary tumour and then liver metastases. METHOD Between 2004 and 2012, patients who… CONTINUE READING
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