Neoadjuvant androgen ablation prior to radiotherapy for prostate cancer: reducing the potential morbidity of therapy.

@article{Zelefsky1997NeoadjuvantAA,
  title={Neoadjuvant androgen ablation prior to radiotherapy for prostate cancer: reducing the potential morbidity of therapy.},
  author={Michael J Zelefsky and Amy Harrison},
  journal={Urology},
  year={1997},
  volume={49 3A Suppl},
  pages={
          38-45
        }
}
OBJECTIVES To determine the impact of neoadjuvant hormonal therapy (NHT) prior to conformal radiotherapy on the reduction of volume of normal tissue structures exposed to high doses of radiation therapy and to evaluate the overall late toxicity and response to treatment among patients treated with this approach. METHODS Among 214 patients treated with neoadjuvant leuprolide acetate and flutamide for 3 months prior to three-dimensional conformal radiotherapy (3D-CRT), 45 patients were… CONTINUE READING