Neo-angiogenesis and the premalignant micro-circulatory augmentation of early colon carcinogenesis.

@article{Tiwari2011NeoangiogenesisAT,
  title={Neo-angiogenesis and the premalignant micro-circulatory augmentation of early colon carcinogenesis.},
  author={Ashish Kumar Tiwari and Susan E Crawford and Andrew J. Radosevich and Ramesh Kumar Wali and Yolanda Stypula and Dhananjay P. Kunte and Nikhil N. Mutyal and Sarah Ruderman and Andrew J. Gomes and Mona L. Cornwell and Mart Angelo De la Cruz and Jeffrey Brasky and Tina P. Gibson and Vadim Backman and Hemant K Roy},
  journal={Cancer letters},
  year={2011},
  volume={306 2},
  pages={205-13}
}
Spectroscopic techniques have demonstrated that in the microscopically normal mucosa, there is an increase in mucosal micro-circulation in patients harboring neoplasia elsewhere in the colon (i.e. marker of field carcinogenesis). However, the physiological and molecular basis of this early increase in blood supply (EIBS) has not been elucidated. We, therefore, investigated the microvessel density (MVD) and angiogenic gene expression in the premalignant colonic mucosa from the well-validated… CONTINUE READING

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We , therefore , investigated the microvessel density ( MVD ) and angiogenic gene expression in the premalignant colonic mucosa from the well - validated azoxymethane ( AOM)-treated rat experimental model of colon carcinogenesis .
We , therefore , investigated the microvessel density ( MVD ) and angiogenic gene expression in the premalignant colonic mucosa from the well - validated azoxymethane ( AOM)-treated rat experimental model of colon carcinogenesis .
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