Nemo-like kinase (NLK) expression in osteoblastic cells and suppression of osteoblastic differentiation.

Abstract

Mitogen-activated protein kinases (MAPKs) regulate proliferation and differentiation in osteoblasts. The vertebral homologue of nemo, nemo-like kinase (NLK), is an atypical MAPK that targets several signaling components, including the T-cell factor/lymphoid enhancer factor (TCF/Lef1) transcription factor. Recent studies have shown that NLK forms a complex… (More)
DOI: 10.1016/j.yexcr.2010.01.023

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