Nemo is an inducible antagonist of Wingless signaling during Drosophila wing development.

@article{Zeng2004NemoIA,
  title={Nemo is an inducible antagonist of Wingless signaling during Drosophila wing development.},
  author={Yi Zeng and Esther M Verheyen},
  journal={Development},
  year={2004},
  volume={131 12},
  pages={2911-20}
}
The cellular events that govern patterning during animal development must be precisely regulated. This is achieved by extrinsic factors and through the action of both positive and negative feedback loops. Wnt/Wg signals are crucial across species in many developmental patterning events. We report that Drosophila nemo (nmo) acts as an intracellular feedback inhibitor of Wingless (Wg) and that it is a novel Wg target gene. Nemo antagonizes the activity of the Wg signal, as evidenced by the… CONTINUE READING

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