Nematode sbRNAs: Homologs of Vertebrate Y RNAs

  title={Nematode sbRNAs: Homologs of Vertebrate Y RNAs},
  author={Ilenia Boria and Andreas R. Gruber and Andrea Tanzer and Stephan H. Bernhart and Ronny Lorenz and Michael M. Mueller and Ivo L. Hofacker and Peter F. Stadler},
  journal={Journal of Molecular Evolution},
Stem-bulge RNAs (sbRNAs) are a group of small, functionally yet uncharacterized noncoding RNAs first described in C. elegans, with a few homologous sequences postulated in C. briggsae. In this study, we report on a comprehensive survey of this ncRNA family in the phylum Nematoda. Employing homology search strategies based on both sequence and secondary structure models and a computational promoter screen we identified a total of 240 new sbRNA homologs. For the majority of these loci we… CONTINUE READING
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