Nelumbinis Semen reverses a decrease in 5-HT1A receptor binding induced by chronic mild stress, a depression-like symptom.

@article{Jang2004NelumbinisSR,
  title={Nelumbinis Semen reverses a decrease in 5-HT1A receptor binding induced by chronic mild stress, a depression-like symptom.},
  author={C G Jang and Moonkyu Kang and Jae-Han Cho and Sun-Bok Lee and Hyuntaek Kim and Soonkwon Park and Jinwoo Lee and Seong-Kyu Park and Moochang Hong and Min Kyu Shin and In-Sup Shim and Hyunsu Bae},
  journal={Archives of pharmacal research},
  year={2004},
  volume={27 10},
  pages={1065-72}
}
Depression is associated with a dysfunctional serotonin (5-hydroxytryptamine; 5-HT) system. More recently, several lines of evidence suggest that an important factor in the development of depression may be a deficit in the function and expression of 5-HT1A receptors. The present study assessed ifNelumbinis Semen (N. s.) had an anti-depression effect through reversing a decrease in 5-HT1A receptor binding in rats with depression-like symptoms induced by chronic mild stress. Using a 5-HT1A… CONTINUE READING

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