Neighborhood Regularized Logistic Matrix Factorization for Drug-Target Interaction Prediction

@inproceedings{Liu2016NeighborhoodRL,
  title={Neighborhood Regularized Logistic Matrix Factorization for Drug-Target Interaction Prediction},
  author={Yong Liu and Min Wu and Chunyan Miao and Peilin Zhao and Xiaoli Li},
  booktitle={PLoS Computational Biology},
  year={2016}
}
In pharmaceutical sciences, a crucial step of the drug discovery process is the identification of drug-target interactions. However, only a small portion of the drug-target interactions have been experimentally validated, as the experimental validation is laborious and costly. To improve the drug discovery efficiency, there is a great need for the development of accurate computational approaches that can predict potential drug-target interactions to direct the experimental verification. In this… CONTINUE READING

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