Negativity of the Basophil Activation Test in Quinolone Hypersensitivity: A Breakthrough for Provocation Test Decision-Making

@article{Rouzaire2011NegativityOT,
  title={Negativity of the Basophil Activation Test in Quinolone Hypersensitivity: A Breakthrough for Provocation Test Decision-Making},
  author={Paul Rouzaire and Audrey Nosbaum and Laure Denis and Françoise Bienvenu and Fr{\'e}d{\'e}ric B{\'e}rard and Gr{\'e}goire Jacques No{\"e}l Cozon and Jacques Michel Jean Bienvenu},
  journal={International Archives of Allergy and Immunology},
  year={2011},
  volume={157},
  pages={299 - 302}
}
Background: Quinolone hypersensitivity reactions are being more frequently reported. Skin tests in investigations of patients are known to not be fully reliable. The provocation test thus remains the gold standard in the definitive diagnosis of allergy, despite the risks involved. The aim of this study was to evaluate basophil activation tests (BATs) in the diagnosis of immediate-type reactions to quinolones. Methods: Thirty-four patients who presented an immediate-type hypersensivity reaction… CONTINUE READING

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