Negative reciprocity between angiotensin II type 1 and dopamine D1 receptors in rat renal proximal tubule cells.

Abstract

Sodium excretion is bidirectionally regulated by dopamine, acting on D1-like receptors (D1R) and angiotensin II, acting on AT1 receptors (AT1R). Since sodium excretion has to be regulated with great precision within a short frame of time, we tested the short-term effects of agonist binding on the function of the reciprocal receptor within the D1R-AT1R… (More)
DOI: 10.1152/ajprenal.90336.2008

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