Negative control of human pancreatic secretion: physiological mechanisms and factors.

  title={Negative control of human pancreatic secretion: physiological mechanisms and factors.},
  author={Jean A. Morisset},
  volume={37 1},
The negative control of pancreatic exocrine secretion in man occurs during the interdigestive and postprandial periods of the digestive cycle. The physiological mechanisms involved include negative feedback mechanisms, well described and accepted in animals, and controlled by the cholecystokinin- and secretin-releasing factors of pancreatic and duodenal origin, along with the active pancreatic proteases present in the upper gut. The presence of these factors and their efficacy in humans… CONTINUE READING


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