Negative Pressure Wound Therapy With Instillation (NPWTi) Better Reduces Post-debridement Bioburden in Chronically Infected Lower Extremity Wounds Than NPWT Alone.

@article{Goss2012NegativePW,
  title={Negative Pressure Wound Therapy With Instillation (NPWTi) Better Reduces Post-debridement Bioburden in Chronically Infected Lower Extremity Wounds Than NPWT Alone.},
  author={Selena G Goss and J Amanda Schwartz and Federico Facchin and Edin Avdagic and Cynthia Gendics and John C. Lantis},
  journal={The journal of the American College of Clinical Wound Specialists},
  year={2012},
  volume={4 4},
  pages={74-80}
}
OBJECTIVE An overabundance of bacteria in the chronic wound plays a significant role in the decreased ability for primary closure. One means of decreasing the bioburden in a wound is to operatively debride the wound for wound bed optimization prior to application of other therapy, such as Negative Pressure Wound Therapy (NPWT). We undertook a prospective pilot study to assess the efficacy of wound bed preparation for a standard algorithm (sharp surgical debridement followed by NPWT) versus one… CONTINUE READING
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