Negative Neurofilament Light and Tau Immunostaining in Frontotemporal Dementia

@article{Sjgren2004NegativeNL,
  title={Negative Neurofilament Light and Tau Immunostaining in Frontotemporal Dementia},
  author={M. Sj{\"o}gren and E. Englund},
  journal={Dementia and Geriatric Cognitive Disorders},
  year={2004},
  volume={17},
  pages={346 - 349}
}
  • M. Sjögren, E. Englund
  • Published 2004
  • Medicine, Psychology
  • Dementia and Geriatric Cognitive Disorders
  • We investigated the immunohistochemical stainability of phosphorylated tau and the light (NFL), intermediate (NFM), and heavy (NFH) neurofilament proteins in postmortem brain tissue from 8 patients with frontotemporal dementia (FTD), for comparison with 6 patients with Alzheimer’s disease (AD), and 6 normal controls. In the FTD group, the neuropathological diagnosis was pure frontal-lobe degeneration of non-Alzheimer type (FLD) in 6 cases and in the remaining 2 cases mixed FLD-AD and frontal AD… CONTINUE READING

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